Author
Duran, S. T., Hassine, Chedia Ben Ali, Burç, M., Güngör, Ö.
Publication Date
2020-06
Publication Place
-
University of Tehran
Subject
Square wave voltammetry, Alpha-lipoic acid, Vanillin, Platinum electrode
Type
Periodical
Language
English
Digital
Yes
Manuscript
No
Library
Özyeğin University
Library Asset ID
2008-4226
Record ID
4414e421-8bea-421a-bdb8-845f8a1d324d
Date
2020-06
Sample Text
In the present study electrochemical detection of alpha-lipoic acid (alpha-LA) was carried out with a poly(Vanillin) modified platinum electrode p(VA)/PtE in Brinton Robinson buffer (BR) solution. The platinum electrode surface's was modified with cyclic voltammetry method. The prepared Pt electrode was characterized by cyclic voltammetry in ferrocyanide and scanning electron microscopy (SEM) images. The number of cycles and scan rate effects were studied using square wave voltammetry (SWV) in BR buffer containing 1 mM alpha-LA. The electrochemical oxidation of alpha-lipoic acid on the modified Pt electrode is influenced by the pH and it is an irreversible reaction in which one electron and one proton are transferred. Electrolyte type and pH effect were studied. The anodic peak current shows a linear increase with alpha-LA concentrations ranging from 0.03 mM to 2.00 mM at pH 5, the detection limit being of 0.025 mM. The alpha-lipoic acid quantification in synthetic urine samples was made by SWV with the modified Pt electrode.
Cilt
12
