Author
Özdemir, Zeynep, Ozdemir, A., Başım, Gül Bahar
Publication Date
2016-11-01
Publication Place
-
Elsevier
Subject
Implantable biomaterials, Surface structuring, Chemical mechanical polishing, Biocompatibility
Type
Periodical
Language
English
Digital
Yes
Manuscript
No
Library
Özyeğin University
Library Asset ID
2-s2.0-84973603567
Record ID
5df206fc-003c-41f3-af17-3cbb9bb52f68
Library Location
Mechanical Engineering
Date
2016-11-01
Notes
Due to copyright restrictions, the access to the full text of this article is only available via subscription.
Sample Text
Modification of the implantable biomaterial surfaces is known to improve the biocompatibility of metallic implants. Particularly, treatments such as etching, sand-blasting or laser treatment are commonly studied to understand the impact of nano/micro roughness on cell attachment. Although, the currently utilized surface modification techniques are known to improve the amount of cell attachment, it is critical to control the level of attachment due to the fact that promotion of bioactivity is needed for prosthetic implants while the cardiac valves, which are also made of titanium, need demotion of cells attachment to be able to function. In this study, a new alternative is proposed to treat the implantable titanium surfaces by chemical mechanical polishing (CMP) technique. It is demonstrated that the application of CMP on the titanium surface helps in modifying the surface roughness of the implant in a controlled manner (inducing nano-scale smoothness or controlled nano/micro roughness). Simultaneously, it is observed that the application of CMP limits the bacteria growth by forming a protective thin surface oxide layer on titanium implants. It is further shown that there is an optimal level of surface roughness where the cell attachment reaches a maximum and the level of roughness is controllable through CMP.
DOI
10.1016/j.msec.2016.06.002
Cilt
68
