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Microcantilever based LoC system for coagulation measurements

Title	Microcantilever based LoC system for coagulation measurements
Author	Çakmak, O., Ermek, E., Kılınç, N., Barış, I., Kavaklı, I. H., Yaralıoğlu, Göksen Göksenin, Urey, H.
Publication Date:	2014
Publication Place	- Chemical and Biological Microsystems Society
Subject	Coagulation time, Blood plasma, Microcantilever, MEMS, PT, aPTT
Type	Document
Language	English
Digital	Yes
Manuscript	No
Library:	Özyeğin University
Library Asset ID	978-097980647-6
Record ID	5d2f115c-452e-4f49-9012-0261f6adb517
Library Location	Electrical & Electronics Engineering
Date	2014
Notes	TÜBİTAK
Sample Text	In this paper, a microcantilever-based system enabling multiple coagulation tests on the same disposable cartridge is demonstrated. The system consists of independent cartridge and reader unit. The actuation of the nickel cantilevers is conducted remotely with an external electro-coil and remote optical read-out is utilized for sensing. Both Prothrombin Time (PT) and activated Partial Thromboplastin Time (aPTT) tests can be conducted on the same cartridge. The system’s repeatability and accuracy is investigated with standard control plasma samples. The results are concordant with the manufacturer’s datasheet. The architecture of the system and the repeatable results makes the system suitable for Point-of-Care applications.

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Özyeğin University

Microcantilever based LoC system for coagulation measurements

Author Çakmak, O., Ermek, E., Kılınç, N., Barış, I., Kavaklı, I. H., Yaralıoğlu, Göksen Göksenin, Urey, H.

Publication Date 2014

Publication Place - Chemical and Biological Microsystems Society

Subject Coagulation time, Blood plasma, Microcantilever, MEMS, PT, aPTT

Type Document

Language English

Digital Yes

Manuscript No

Library Özyeğin University

Library Asset ID 978-097980647-6

Record ID 5d2f115c-452e-4f49-9012-0261f6adb517

Library Location Electrical & Electronics Engineering

Date 2014

Notes TÜBİTAK

Sample Text In this paper, a microcantilever-based system enabling multiple coagulation tests on the same disposable cartridge is demonstrated. The system consists of independent cartridge and reader unit. The actuation of the nickel cantilevers is conducted remotely with an external electro-coil and remote optical read-out is utilized for sensing. Both Prothrombin Time (PT) and activated Partial Thromboplastin Time (aPTT) tests can be conducted on the same cartridge. The system’s repeatability and accuracy is investigated with standard control plasma samples. The results are concordant with the manufacturer’s datasheet. The architecture of the system and the repeatable results makes the system suitable for Point-of-Care applications.