LoC sensor array platform for real-time coagulation measurements

Name: LoC sensor array platform for real-time coagulation measurements
Author: Cakmak, O., Kılınç, N., Ermek, E., Mostafazadeh, A., Elbuken, Ç., Yaralıoğlu, Göksen Göksenin, Urey, H.

İsim	LoC sensor array platform for real-time coagulation measurements
Yazar	Cakmak, O., Kılınç, N., Ermek, E., Mostafazadeh, A., Elbuken, Ç., Yaralıoğlu, Göksen Göksenin, Urey, H.
Basım Tarihi:	2014
Basım Yeri	- IEEE
Konu	Coagulation, Lab-on-a-chip, Microfluidics, Microsensors
Tür	Belge
Dil	İngilizce
Dijital	Evet
Yazma	Hayır
Kütüphane:	Özyeğin Üniversitesi
Demirbaş Numarası	978-1-4799-3509-3
Kayıt Numarası	71016d41-a529-42c2-9d87-0de168342572
Lokasyon	Electrical & Electronics Engineering
Tarih	2014
Notlar	Due to copyright restrictions, the access to the full text of this article is only available via subscription.
Örnek Metin	This paper reports a MEMS-based sensor array enabling multiple clot-time tests in one disposable microfluidic cartridge using plasma. The versatile LoC (Lab-on-Chip) platform technology is demonstrated here for real-time coagulation tests (activated Partial Thrompoblastin Time (aPTT) and Prothrombin Time (PT)). The system has a reader unit and a disposable cartridge. The reader has no electrical connections to the cartridge, which consists of multiple microfluidic channels and MEMS microcantilevers placed in each channel. Microcantilevers are made of electro-plated nickel and actuated remotely using an external electro-coil. The read-out is also conducted remotely by a laser and the phase of the MEMS oscillator is monitored real-time. The system is capable of monitoring coagulation time with a precision estimated at 0.1sec.
DOI	10.1109/MEMSYS.2014.6765643

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LoC sensor array platform for real-time coagulation measurements

Yazar Cakmak, O., Kılınç, N., Ermek, E., Mostafazadeh, A., Elbuken, Ç., Yaralıoğlu, Göksen Göksenin, Urey, H.

Basım Tarihi 2014

Basım Yeri - IEEE

Konu Coagulation, Lab-on-a-chip, Microfluidics, Microsensors

Tür Belge

Dil İngilizce

Dijital Evet

Yazma Hayır

Kütüphane Özyeğin Üniversitesi

Demirbaş Numarası 978-1-4799-3509-3

Kayıt Numarası 71016d41-a529-42c2-9d87-0de168342572

Lokasyon Electrical & Electronics Engineering

Tarih 2014

Notlar Due to copyright restrictions, the access to the full text of this article is only available via subscription.

Örnek Metin This paper reports a MEMS-based sensor array enabling multiple clot-time tests in one disposable microfluidic cartridge using plasma. The versatile LoC (Lab-on-Chip) platform technology is demonstrated here for real-time coagulation tests (activated Partial Thrompoblastin Time (aPTT) and Prothrombin Time (PT)). The system has a reader unit and a disposable cartridge. The reader has no electrical connections to the cartridge, which consists of multiple microfluidic channels and MEMS microcantilevers placed in each channel. Microcantilevers are made of electro-plated nickel and actuated remotely using an external electro-coil. The read-out is also conducted remotely by a laser and the phase of the MEMS oscillator is monitored real-time. The system is capable of monitoring coagulation time with a precision estimated at 0.1sec.

DOI 10.1109/MEMSYS.2014.6765643