Improving blood products supply through donation tailoring

Name: Improving blood products supply through donation tailoring
Author: Özener, Okan Örsan, Ekici, Ali, Göktürk, Elvin Çoban

İsim	Improving blood products supply through donation tailoring
Yazar	Özener, Okan Örsan, Ekici, Ali, Göktürk, Elvin Çoban
Basım Tarihi:	2019-02
Basım Yeri	- Elsevier
Konu	Blood supply chain, Blood products, Multicomponent apheresis, Donation tailoring, Column generation
Tür	Süreli Yayın
Dil	İngilizce
Dijital	Evet
Yazma	Hayır
Kütüphane:	Özyeğin Üniversitesi
Demirbaş Numarası	0305-0548
Kayıt Numarası	e542ba63-c242-4d15-8090-f3a13fad41e9
Lokasyon	Industrial Engineering
Tarih	2019-02
Notlar	TÜBİTAK
Örnek Metin	Recent technological advances, called Multicomponent Apheresis, allow tailoring the blood donations based on the demand and current inventory levels of blood products. Different from the most common type of blood donation (known as Whole Blood Donation), Multicomponent Apheresis allows the donation of one or more transfusable units of one or more blood products. Considering the changing demand for blood products during a planning horizon, deferral times, perishability of blood products, and limited donor pool, Multicomponent Apheresis provides an opportunity for increased donor utilization and hence a better managed blood supply chain. However, except some general guidelines proposed by blood donation organizations, the literature lacks analytical tools which can be used to fully explore the potential advantages of Multicomponent Apheresis, including the reduction in donation related costs and better utilization of the donor pool. In this paper, we develop models and solution approaches for tailoring the donations in order to quantify the potential benefits of Multicomponent Apheresis. More specifically, we define the Blood Donation Tailoring Problem where the objective is to minimize the total donation, inventory and disposal costs of blood products while satisfying the demand for blood products during a planning horizon by determining the donation schedule of a given donor pool. We develop a mathematical model and a column generation approach to tailor the donations. We also propose a more practical rule-of-thumb which can be easily implemented by the blood donation organizations. We compare the performances of the proposed approaches against a lower bound and the current practice at an apheresis facility. Finally, we also show that the proposed column generation approach can easily be modified to handle realistic aspects of the problem including stock-out and donor eligibility/preferences.
DOI	10.1016/j.cor.2018.09.003
Cilt	102

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Improving blood products supply through donation tailoring

Yazar Özener, Okan Örsan, Ekici, Ali, Göktürk, Elvin Çoban

Basım Tarihi 2019-02

Basım Yeri - Elsevier

Konu Blood supply chain, Blood products, Multicomponent apheresis, Donation tailoring, Column generation

Tür Süreli Yayın

Dil İngilizce

Dijital Evet

Yazma Hayır

Kütüphane Özyeğin Üniversitesi

Demirbaş Numarası 0305-0548

Kayıt Numarası e542ba63-c242-4d15-8090-f3a13fad41e9

Lokasyon Industrial Engineering

Tarih 2019-02

Notlar TÜBİTAK

Örnek Metin Recent technological advances, called Multicomponent Apheresis, allow tailoring the blood donations based on the demand and current inventory levels of blood products. Different from the most common type of blood donation (known as Whole Blood Donation), Multicomponent Apheresis allows the donation of one or more transfusable units of one or more blood products. Considering the changing demand for blood products during a planning horizon, deferral times, perishability of blood products, and limited donor pool, Multicomponent Apheresis provides an opportunity for increased donor utilization and hence a better managed blood supply chain. However, except some general guidelines proposed by blood donation organizations, the literature lacks analytical tools which can be used to fully explore the potential advantages of Multicomponent Apheresis, including the reduction in donation related costs and better utilization of the donor pool. In this paper, we develop models and solution approaches for tailoring the donations in order to quantify the potential benefits of Multicomponent Apheresis. More specifically, we define the Blood Donation Tailoring Problem where the objective is to minimize the total donation, inventory and disposal costs of blood products while satisfying the demand for blood products during a planning horizon by determining the donation schedule of a given donor pool. We develop a mathematical model and a column generation approach to tailor the donations. We also propose a more practical rule-of-thumb which can be easily implemented by the blood donation organizations. We compare the performances of the proposed approaches against a lower bound and the current practice at an apheresis facility. Finally, we also show that the proposed column generation approach can easily be modified to handle realistic aspects of the problem including stock-out and donor eligibility/preferences.

DOI 10.1016/j.cor.2018.09.003

Cilt 102