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Metal-organic frameworks for biomedical applications

İsim Metal-organic frameworks for biomedical applications
Yazar Gülçay, Ezgi, Fındıkçı, İlknur Eruçar
Basım Tarihi: 2020
Basım Yeri - Elsevier
Konu Biomedical application, Drug delivery, Drug storage, Metal-organic framework, Molecular simulations
Tür Kitap
Dil İngilizce
Dijital Evet
Yazma Hayır
Kütüphane: Özyeğin Üniversitesi
Demirbaş Numarası 978-0-12-817650-4
Kayıt Numarası 0b939c1d-9c37-4165-aacd-0f637a05a676
Lokasyon Natural and Mathematical Sciences
Tarih 2020
Örnek Metin Metal-organic frameworks (MOFs) have received significant interest in the recent years as promising candidates for biomedical applications due to their high porosities and tunable surface characteristics. The rational design and synthesis of MOFs provide unique physical and chemical structures that make them potential materials for drug storage and drug delivery; biologically important gas storage such as nitric oxide, hydrogen sulfide, and oxygen; imaging; and sensing. The aim of this chapter is to outline the recent progress in biomedical applications of MOFs, mainly focusing on drug storage and drug delivery applications. First, MOFs were briefly introduced and then both experimental and computational studies with emphasis on their potential applications in drug storage, biomedical gas storage, and drug delivery were reviewed. Critical issues such as toxicity, size, shape, and biological stability were also discussed. Finally, current opportunities and challenges of using MOFs in biomedicine were addressed and some future trends were suggested.
DOI 10.1016/B978-0-12-817650-4.00006-1
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Metal-organic frameworks for biomedical applications

Yazar Gülçay, Ezgi, Fındıkçı, İlknur Eruçar
Basım Tarihi 2020
Basım Yeri - Elsevier
Konu Biomedical application, Drug delivery, Drug storage, Metal-organic framework, Molecular simulations
Tür Kitap
Dil İngilizce
Dijital Evet
Yazma Hayır
Kütüphane Özyeğin Üniversitesi
Demirbaş Numarası 978-0-12-817650-4
Kayıt Numarası 0b939c1d-9c37-4165-aacd-0f637a05a676
Lokasyon Natural and Mathematical Sciences
Tarih 2020
Örnek Metin Metal-organic frameworks (MOFs) have received significant interest in the recent years as promising candidates for biomedical applications due to their high porosities and tunable surface characteristics. The rational design and synthesis of MOFs provide unique physical and chemical structures that make them potential materials for drug storage and drug delivery; biologically important gas storage such as nitric oxide, hydrogen sulfide, and oxygen; imaging; and sensing. The aim of this chapter is to outline the recent progress in biomedical applications of MOFs, mainly focusing on drug storage and drug delivery applications. First, MOFs were briefly introduced and then both experimental and computational studies with emphasis on their potential applications in drug storage, biomedical gas storage, and drug delivery were reviewed. Critical issues such as toxicity, size, shape, and biological stability were also discussed. Finally, current opportunities and challenges of using MOFs in biomedicine were addressed and some future trends were suggested.
DOI 10.1016/B978-0-12-817650-4.00006-1
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