The Effect of 10 Weeks Combined Training in Water on Immunosenescence in Elderly Rats

Name: The Effect of 10 Weeks Combined Training in Water on Immunosenescence in Elderly Rats
Author: Mohammad Jahanmahin

İsim	The Effect of 10 Weeks Combined Training in Water on Immunosenescence in Elderly Rats
Yazar	Mohammad Jahanmahin
Konu	aged, circuit-based exercise, combined training, immunosenescence, t lymphocytes
Tür	Belge
Dil	Belirlenmemiş dil
Dijital	Evet
Yazma	Hayır
Kütüphane:	Belfast Kraliçe Üniversitesi Kütüphaneleri
Demirbaş Numarası	ISSN: 1027-7595, EISSN: 1735-854X, DOI: 10.48305/jims.v40.i694.0890
Kayıt Numarası	cdi_doaj_primary_oai_doaj_org_article_374a4c22fb1e43cd950663ba93e6e30d
Açıklama	Background: A complex of restricted naïve lymphocytes in conjunction with an age-associated accumulation of senescent T cells and/or thymic involution are major contributors to immunosenescence, which can be modulated by exercise training. Therefore, the present study aims to investigate 10 weeks of combined training in water on immunosenescence in elderly rats.Methods: 16 rats for 24 months with mean weight 320 ± 5gr were randomly distributed into a control group (n = 8) and combined training (n = 8). Combined training was performed in 4 sessions per week (two endurance days and two resistance days) in a container with dimensions of 50×50×100 centimeter with water at 30 ± 1 ºC. Data were analyzed by one-way ANOVA test.Findings: A significant decrease was observed in training groups than control in thymus weight and indicators related to senescent TCD8+ and senescent naïve TCD8+ and TCD4+ (P = 0.01), as well as, there was a significant increase in indicators related to CD4+ and CD8+ and naïve TCD8+ and TCD4+ lymphocytes (P = 0.01). While wasn't observed significant difference between CD4+/CD8+ ratio and indicators related to senescent TCD4+ (P = 0.48 and P = 0.19, respectively).Conclusion: The results of this study suggest that combined training in water is a safe activity for the elderly to improve the immune system and reduction of senescence-prone T cells.
Şuna bir parçasıdır	Majallah-i dānishkadah-i pizishkī-i Iṣfahān. (Online), 1401-10, Vol.40 (694), p.890-899
Kaynak	DOAJ Directory of Open Access Journals

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The Effect of 10 Weeks Combined Training in Water on Immunosenescence in Elderly Rats

Yazar Mohammad Jahanmahin

Konu aged, circuit-based exercise, combined training, immunosenescence, t lymphocytes

Tür Belge

Dil Belirlenmemiş dil

Dijital Evet

Yazma Hayır

Kütüphane Belfast Kraliçe Üniversitesi Kütüphaneleri

Demirbaş Numarası ISSN: 1027-7595, EISSN: 1735-854X, DOI: 10.48305/jims.v40.i694.0890

Kayıt Numarası cdi_doaj_primary_oai_doaj_org_article_374a4c22fb1e43cd950663ba93e6e30d

Açıklama Background: A complex of restricted naïve lymphocytes in conjunction with an age-associated accumulation of senescent T cells and/or thymic involution are major contributors to immunosenescence, which can be modulated by exercise training. Therefore, the present study aims to investigate 10 weeks of combined training in water on immunosenescence in elderly rats.Methods: 16 rats for 24 months with mean weight 320 ± 5gr were randomly distributed into a control group (n = 8) and combined training (n = 8). Combined training was performed in 4 sessions per week (two endurance days and two resistance days) in a container with dimensions of 50×50×100 centimeter with water at 30 ± 1 ºC. Data were analyzed by one-way ANOVA test.Findings: A significant decrease was observed in training groups than control in thymus weight and indicators related to senescent TCD8+ and senescent naïve TCD8+ and TCD4+ (P = 0.01), as well as, there was a significant increase in indicators related to CD4+ and CD8+ and naïve TCD8+ and TCD4+ lymphocytes (P = 0.01). While wasn't observed significant difference between CD4+/CD8+ ratio and indicators related to senescent TCD4+ (P = 0.48 and P = 0.19, respectively).Conclusion: The results of this study suggest that combined training in water is a safe activity for the elderly to improve the immune system and reduction of senescence-prone T cells.

Şuna bir parçasıdır Majallah-i dānishkadah-i pizishkī-i Iṣfahān. (Online), 1401-10, Vol.40 (694), p.890-899

Kaynak DOAJ Directory of Open Access Journals